肺炎衣原体感染与偏头痛的关系

Association between chronic chlamydia pneumoniae infection and migraine

目的探讨慢性肺炎衣原体(CPn)感染与偏头痛的关系。方法所有病例分为观察组(56例)与对照组(30例)。肺炎衣原体血清特异性IgG、IgM抗体采用酶联免疫吸附试验法,血清胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白(HDL-C)浓度检测采用全自动生化仪。结果观察组和对照组肺炎衣原体感染率分别为62.50%和36.67%,差异有统计学意义(P<0.05)。结论偏头痛患者肺炎衣原体感染率明显增高,肺炎衣原体感染与偏头痛有关,可能是偏头痛发作的病因之一,深入研究可能探索偏头痛的发病机制及防治新途径。

Objective To investigate the association between chronic chlamydia pneumonia （CPn） infection and migraine. Methods All patients were divided into two groups： the observation group （56 cases） and the control group （30 cases）. CPn IgG and CPn IgM were detected by enzyme linked immunosorbent assay （ELISA） method. The serum cholesterol （TC）, triglyceride（TG） and high density lipoprotein（HDL-C） were detected with automatic biochemistry meter. Results The chronic CPn infection rates of the observation group and the control group respectively were 62.50 % and 36.67 %. The difference between the two groups was statistically significant（P〈0. 05）. Conclusion The CPn infection rates of migraine patients are obviously elevated. The chronic CPn infection is relative to migraine and possibly is one of the etiological factors of migraine attack. Penetrating research is respected to explore the pathogen and a new prevention and cure path of migraine.