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睡眠呼吸暂停低通气或间歇低氧与高血压 被引量：1

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摘要 阻塞性睡眠呼吸暂停低通气综合征（OSAHS）是发病率较高、合并症较多的睡眠呼吸疾患。众多的临床和流行病学研究结果表明，OSAHS是高血压发病的独立危险因素^[1]，其机制尚未完全阐明。患者睡眠中因呼吸暂停引起的反复短暂缺氧为间歇低氧（intermittenthypoxia），这是OSAHS的主要病理生理学特点和损伤机制。近年来越来越多的研究结果显示，间歇低氧与OSAHS患者高血压的发生密切相关。
作者 袁志明 陈宝元
机构地区 天津医科大学总医院呼吸科
出处 《中华结核和呼吸杂志》 CAS CSCD 北大核心 2007年第12期944-945,共2页 Chinese Journal of Tuberculosis and Respiratory Diseases
关键词 阻塞性睡眠呼吸暂停低通气综合征 间歇低氧 高血压 OSAHS 独立危险因素 生理学特点 流行病学 损伤机制
分类号 R56 [医药卫生—呼吸系统] R544.1 [医药卫生—心血管疾病]
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参考文献20

  • 1Phillips CL, Cistulli PA. Obstructive sleep apnea and hypertension, epidemiology, mechanisms and treatment effects. Minerva Med, 2006,97:299-312.
  • 2Leuenberger UA, Brubaker D, Quraishi S, et al. Effects of intermittent hypoxia on sympathetic activity and blood pressure in humans. Auton Neurosci, 2005,121:87-93.
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二级参考文献16

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中华结核和呼吸杂志
2007年 第12期

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