广东省消除丝虫病后监测效果评价

Epidemic Surveillance after the Elimination of Filariasis in Guangdong Province

目的了解消除丝虫病后的流行动态,探讨消除丝虫病后的监测方法。方法采用血清学结合病原学的监测方法,对可能遗留有残存传染源的地区和重点流动人口进行监测;对原微丝蚴血症者进行追踪观察。结果2002-2006年共血检12267人,未发现微丝蚴血症者;对重点流动人口血检4390人,未检出微丝蚴血症者;2004年对来自安徽等省的人群检测丝虫IgG4,结果1例抗体阳性,血检为阴性;对57个村原微丝蚴血症者1087人追踪观察,没有发现微丝蚴血症者。在35个县进行慢性丝虫病调查55746人,发现有体征症状者24例(其中下肢象皮肿13例、乳糜尿10例、鞘膜积液1例),患病率为0.04%。对45例慢性丝虫病患者给予治疗和处理(其中乳糜尿31例、象皮肿14例),结果乳糜尿复发率为22.58%,象皮肿患者感染发炎(淋巴管炎)的次数明显减少。结论广东省消除丝虫病的成果巩固,内源性传染源存在的可能性极小。

Objective To understand the trends of endemic situation after the elimination of filariasis in Guangdong province. Method Parasitologieal and serological methods were used to examine if there stiU remained infectious source in those areas. Follow up observations on the former miemfilaremia eases in the former endemic areas were conducted. Result From 2001 to 2006, blood examination were made on 12267 people in the areas which were suspected as residual epidemic and 4390 floating population in the focus areas. No miemfilaremia ease was found. In the follow up examinations for 1087 former miemfilaremia eases in 6 counties, no positive ease was found. In 2004, 2125 individuals of the floating population in Dongguan city were diagnosed for filariasis by ELISA and one person was positive. And this one showed a negative result in blood examination. The chronic filariasis patients were investigated in 35 counties, with a positive rate of 0.04%. Conclusion With the implementation of the interference of the infection source, the elimination of filariasis is achieved and the number of filariasis eases remains consistently low in Guangdong.