妊娠晚期孕妇凝血功能检测与分析

Detection and analysis of blood coagulation function in late-pregnant women

目的探讨妊娠晚期孕妇凝血功能检测的临床意义。方法采用Sysmex-1500型全自动凝血分析仪测定280例妊娠晚期孕妇(观察组)及140例健康育龄妇女(对照组)的凝血酶原时间(PT)、国际化标准比值(INR)、活化部分凝血活酶时间(APTT)、凝血酶时间(TT)、纤维蛋白原(Fbg),并进行分析比较。结果观察组的PT、INR、APTT均较对照组明显缩短,Fbg高于对照组,P<0.01;而两组TT差异无统计学意义(P>0.05)。结论妊娠晚期妇女血液处于高凝状态。检测其凝血功能,对预防或早期治疗弥散性血管内凝血(DIC)有一定的帮助。

Objective To investigate the clinical significance of blood coagulation function detection in latepregnant women. Methods Sysmex-1500 automatic analyzer was applied to determinating routine coagulation function parameters including prothrombin time （PT）, international normalized ratio （INR）, activated partial thromboplasting time （APTT）, thrombin time （TT） and fibrinogen （Fbg） in 280 late-pregnant women （served as observation group） and 140 healthy controls （served as control group）. Results As compared with that of control group, PT, INR and APTT in observation group were decreased significantly while Fbg was more elvated （P〈0.01）. There was no significant difference of TT between the two groups（P〉0.05）. Conclusion The late-pregnant women are in a hypercoagulation state. The detection of blood coagulation function plays an important role in the prevention and early tratment of DIC.