用“B&G System”检测与校正部分生化指标研究

The study of detecting and correcting part of biochemical markers by"B&G System"

目的验证新开发的"B&G System"在检测部分生化指标方面的准确性。方法先后用日立7170S全自动生化分析仪(7170S)与"B&G System"测量同一份血清标本的肌酐(SCr)、尿素氮(BUN)、尿酸(SUA)、钙(Ca)或磷(P)等生化指标;每项生化指标根据7170S测量值分为正常组与异常组,比较用两种方法所测的每项生化指标各组测量值间差异有无统计学意义,如有,则对"B&G System"该项生化指标检测程序予以校正,并比较校正后用两种方法所测该项生化指标值间的差异有无统计学意义。结果两种方法所测异常组SCr值、每组BUN值、每组SUA值与每组P值间差异无统计学意义(P>0.05),而正常组SCr值、两组Ca值间差异则有统计学意义(P<0.05);对"B&G System"校正后,两种方法所测正常组SCr值、两组Ca值间差异无统计学意义(P>0.05)。结论校正后的"B&G System"可准确测量SCr、BUN、SUA、Ca、P等生化指标,值得临床应用推广。

Objective To verify the accuracy of detecting part of biochemical markers of the new ＂B＆G System＂. Methods Blood serum creatinine（SCr）, urea nitrogen（BUN）,serum uric acid（UA）, Ca or P of the same serum example were detected by ＂B＆G System＂ and Hitachi 7170S automatic biochemistry analysis instrument （7170S） respectively. Each biochemical marker was divided into two teams on the basis of measure values of 7170S, and then measure values of two methods were compared. If there were significant differences, the biochemical markers＇s detection program of ＂B＆G System＂ was corrected,and then measure values of two methods of corresponding biochemical markers were compared. Results Two methods＇ measure values of SCr of abnormal team, BUN of each team,SUA of each team and P of each team weren＇t significantly different, measure values of SCr of normal team,Ca of two teams were significantly different. After corrected ＂B＆G System＂, two methods＇ measure values of SCr of normal team,Ca of two teams weren＇t significantly different. Conclusion ＂B＆G System＂ through correction could accurately detect biochemical markers,and it＇s worth applicating in clinic.