摘要
通过间溴苯甲醚与2－二甲胺甲基环己酮反应制得1-间甲氧苯基-2-二甲胺甲基环己醇，对其分离得到相应的顺反异构体．对反应的立体化学进行了分析，并用13CNMR谱确定了顺反异构体的构型．
The reaction of 2-(dimethylaminomethyl) cyclohexanone with m-anisyl magne-sium bromlde yielded the title compound as a mixture of Z- and E-isomers, which were sepa-rated into their pure component by fractional crystallization. Their configurations were de-termined by 13C NMR spectra. The stereochemistry of the reaction was discussed.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1997年第6期902-905,共4页
Chemical Journal of Chinese Universities
关键词
间甲氧苯基
二甲胺甲基
环己醇
合成
顺反异构体
1-(m-Methoxyphenyl)-2-(dimethylaminomethyl)-cyclohexanol, Synthesis, Separation, Structure
