摘要
Monometalloporphyrin and p-oxo-bismetalloporphyrin compounds of metal iron,manganese and cobalt were synthesized, and used as the model compounds of cytochrome P-450 monooxygenase in catalytic oxidation of cyclohexane with iodosobenzene. The influence of the addition of magnetic field on the catalytic properties of these metalloporphyrins was in-spected. The studies reveal that the influence of the addition of magnetic field on the catalyt-ic behavior of other metalloporphyrins does not go beyond 37% except monoironporphyrin.But the addition of magnetic field makes the reaction yield of cyclohexane oxidation catalyzed by monoironporphyrin be increased to 53%, and makes the rate of reaction be twice as much. This fact means that the catalytic processes of cytochrome P-450 monooxygenase in human bodies may be bound up with earth magnetic field closely. This discovery has singular meaning to unlock the mystery of biosphere consisting of human and earth.
Monometalloporphyrin and p-oxo-bismetalloporphyrin compounds of metal iron,manganese and cobalt were synthesized, and used as the model compounds of cytochrome P-450 monooxygenase in catalytic oxidation of cyclohexane with iodosobenzene. The influence of the addition of magnetic field on the catalytic properties of these metalloporphyrins was in-spected. The studies reveal that the influence of the addition of magnetic field on the catalyt-ic behavior of other metalloporphyrins does not go beyond 37% except monoironporphyrin.But the addition of magnetic field makes the reaction yield of cyclohexane oxidation catalyzed by monoironporphyrin be increased to 53%, and makes the rate of reaction be twice as much. This fact means that the catalytic processes of cytochrome P-450 monooxygenase in human bodies may be bound up with earth magnetic field closely. This discovery has singular meaning to unlock the mystery of biosphere consisting of human and earth.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1997年第6期906-907,共2页
Chemical Journal of Chinese Universities
基金
国家自然科学基金
机械部优秀人才基金
