干细胞治疗心肌梗死的研究概况

Brief accout of stem cell application in treating myocardial infarction

心肌梗死引起的瘢痕形成和并发的心肌功能降低,可继而导致心室重构和心力衰竭的发生。因此,恢复受损心肌组织功能的治疗必不可少,以干细胞为基础的心肌再生与修复治疗最终能够避免心室重构的进程和心力衰竭的发生。心脏疾病的细胞治疗是一个快速发展的领域,但目前仍然存在许多难以解决的问题。

Myocardial infarction is one of the main factors causing heart failure and is associated with a high rate of morbidity and mortality in the developing countries. Due to infracted cardiac muscles, heart function will aggravate and myocardium will remodel leading to exacerbation of the disease. Current treatment modalities may not be adequate to prevent myocardial remodeling. It is necessary to explore a new approach to restore the damaged myocardium. Stem cell-based therapy is developing rapidly and has been used in the field of cardiovascular disease. There are many problems still to be solved.