期刊文献+

电焊工人唾液锰和血清锰及尿锰的改变 被引量:6

原文传递
导出
摘要 目的探讨唾液锰是否可作为锰接触的生物检测指标。方法选择电焊锰作业工人49名,其中高浓度接触组21人、低浓度接触组28人,采用电感耦合等离子体质谱法(ICP-MS)测定唾液锰和血清锰,用石墨炉原子吸收分光光度法测定尿锰。结果高浓度接触组的车间空气锰浓度达2.21 mg/m^3,低浓度接触组为0.24 mg/m^3。接触组的唾液锰和血清锰分别为(4.45±2.17)、(4.64±1.30)μg/L,均明显高于对照组[分别为(3.04±1.40)、(2.70±1.50)μg/L],差异有统计学意义(P<0.01),尿锰略高于对照组,但差异无统计学意义(P>0.05)。高浓度接触组的唾液锰和血清锰升高者分别为85.71%和100.00%,升高均值为3.04和3.00μg/L;低浓度接触组的唾液锰和血清锰升高者为71.43%和89.29%,升高均值为1.04和1.40μg/L。唾液锰和血清锰未见伴随工龄的升高趋势。结论唾液锰与血清锰测定均可反映工人的近期锰接触状况,尿锰的变化不敏感。唾液锰测定方便、准确,可作为新的生物检测指标。
出处 《中华劳动卫生职业病杂志》 CAS CSCD 北大核心 2007年第12期744-746,共3页 Chinese Journal of Industrial Hygiene and Occupational Diseases
  • 相关文献

参考文献18

  • 1Myers JE, Thompson ML, Ramushu S, et al. The nervous system effects of occupational exposure on workers in a South African manganese smelter. Neurotoxicology, 2003, 24: 885-894.
  • 2Narmandin L, Hazell AS. Manganese neurotoxicity :an update of pathophysiologic mechanisms. Metab Brain Dis, 2002, 17: 375- 387.
  • 3杜旭芹,王涤新,冯先进.血清和唾液中五种微量元素的电感耦合等离子体质谱测定法[J].中华预防医学杂志,2006,40(1):53-54. 被引量:12
  • 4Warnakulasuriya S, Soussi T, Maher R, et al. Expression of p53 in oral squamous cell carcinoma is associated with the presence of IgG and IgA p53 autoantibodies in sera and saliva of the patients.J Pathol, 2000,192: 52-57.
  • 5Fliss MS, Usadel H, Caballero OL, et al. Facile detection of mitochondfial DNA mutations in tumors and bodily fluids. Science, 2000, 287: 2017-2019.
  • 6Zhlevachevsky NG, Nomokonova NY, Beklemishev AB, et al. Dynamic study of HBsAg and HBeAg in saliva samples from patients with hepatitis B infection: diagnostic and epidemiological significance. J Med Virol, 2000, 61: 433-438.
  • 7King SD, Wynter SH, Bain BC, et al. Comparison of testing saliva and serum for detection of antibody to human immunodeficiency virus in Jamaica, West Indies. J Clin Virol, 2000,19:157-161.
  • 8Dumortier G, Lochu A, Zerrouk AP, et al. Whole saliva and plasma levels of clozapine and desmethylclozapine. J Clin Pharm Ther, 1998, 23: 35-40.
  • 9Findling JW, Raft H. Newer diagnostic techniques and problems in Cushing's disease.Endocrinol Metab Clin North Am, 1999, 28:191- 210.
  • 10Omokhodion FO, Crockford GW. Lead in sweat and its relationship to salivary and urinary levels in normal healthy subjects. Sci Total Environ, 1991, 103: 113-122.

二级参考文献10

共引文献19

同被引文献54

引证文献6

二级引证文献19

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部