平阳霉素治疗口腔颌面部静脉畸形的临床观察

The role of intraleisonal pingyangmycin in the treatment of maxilla and facial venous malformation

目的观察平阳霉素治疗口腔颌面部静脉畸形的临床效果。方法160例确诊的颌面部静脉畸形患者,随机分为2组,每组80例。分别于瘤腔注射平阳霉素+地塞米松和鱼肝油酸钠。结果注射平阳霉素+地塞米松组总有效率为92.5%,治愈率为80%;注射鱼肝油酸钠组总有效率为62.5%,治愈率为42.5%。两组比较有显著性差异(P<0.01)。结论平阳霉素+地塞米松局部注射是治疗颌面部静脉畸形的一种安全有效的方法。

Objective To explore the role of intraleisonal pingyangmycin in the treatment of maxilla and facial vascular malformation. Methods A total of 160 cases with vein malformation were divided into two groups randomly, and were injected pinyangmycin and sod morrhuate, respectively. Results The size of the swelling reduced by 50% or more in 74 patients （92.5%） and by 75% or more in 64 patients （80%） in pinyangmycin group; the size of the swelling reduced by 50 % or more in 50 patients （62.5 % ） and by 75 % or more in 34 patients （42.5 % ） in sod morrhuate group; there was a significant difference in the two groups. Conclusion Intralesional injection of pinyangmycin is an easy, safe, and effective therapeutic method in venous malformation.