摘要
目的:探讨老年非ST段抬高急性冠脉综合征(NSTE-ACS)患者不同治疗策略与心肌梗死溶栓试验(TIMI)危险评分的关系。方法:将2003年8月至2005年5月老年NSTE-ACS患者共242例,随机分为早期保守治疗组和早期有创干预组,再根据TIMI危险评分分为低分组、中分组、高分组。随访30天与6个月的复合心血管事件,评价不同TIMI危险评分对两种治疗措施的影响。结果:早期有创干预组随访30天及6个月复合心血管事件减少(P<0.05),早期有创干预组随访30天及6个月TIMI危险评分高分组、中分组患者复合心血管事件发生率明显低于随访同期早期保守治疗组(P<0.05),但低分组间患者复合心血管事件发生率差异无统计学意义(P>0.05)。结论:在TIMI危险评分高及中分组NSTE-ACS患者中,早期有创干预较保守治疗组能显著降低心血管事件,改善预后。
Objective: To investigate the relationship between thrombolysis in myocardial infaction(TIMI) risk score and efficacy of different treatment strategies in old patients with non ST - segment elevation acute coronary syndromes(NSTE - ACS). Methods: From Aug. 2003 to May 2005. 242 old patients with NSTE - ACS were randomly assigned to early conservative strategy or early invasive strategy group. Furthermore, low, moderate and high TIMI risk score were defined according to the TIMI risk score. The combined cardiovascular events were analyzed within follow - up 30 days and 6 months and related to the TIMI risk score at admission.Results: The combined cardiovascular events of 30 days and 6 months were singificantly lower in early invasive strategy group compared with early conservative strategy group. It dicated that early conservative strategy could decrease the 30 d incidence of the combined end piont events in patients with high and moderate TIMI risk score (P 〈 0.05), but the incidence was similar between the two different strategies in patients with low TIMI risk score. Conclusions: Early invasive strategy may significantly reduce combined cardiovascular events in NSTE - ACS old patients with moderate and high TIMI risk score compared with early conservative strategy.
出处
《中国医药导刊》
2007年第6期470-471,共2页
Chinese Journal of Medicinal Guide
关键词
急性冠脉综合征
危险因素
预后
Acute coronary syndrome
Risk factors
Risk assessment
Prognosis