甲状腺全切除术治疗良性甲状腺疾病临床价值的研究

Clinical research about the value of total thyroidectomy for benign thyroid disease

目的:探讨甲状腺全切除术治疗甲状腺良性疾病的价值及临床意义。方法:回顾分析我院2005年3月～2007年3月收治的169例行甲状腺全切除术的甲状腺良性疾病患者临床病理资料,并对其术后并发症进行分析总结。结果:首次甲状腺全切除术后暂时性甲状旁腺功能低下和暂时性喉返神经损伤的发生率分别为0.76%和1.52%,再次手术的并发症明显增高,分别为40.54%和32.43%,P<0.01。术后患者均未发生永久性甲状旁腺功能低下和永久性喉返神经损伤。结论:甲状腺全切除术治疗良性甲状腺疾病能避免组织残留所致的病变复发和癌变,降低再手术率,且首次手术较再次手术的并发症率低,但需在术中精细操作。

Objective： To investigate the value and clinical significance of total thyroidectomy performed for benign thyroid disease. Methods： Retrospectively analysis the 169 cases data that patients with benign thyroid disease were treated with total thyroidectomy from March 2005 to March 2007 in our hospital, and the postoperative complications were analyzed and summarized. Results： With primary total thyroidectomy, the incidences of transient hypocalcaemia and transient recurrent laryngeal nerve paralysis were 0.76% and 1.52 % respectively. The incidences after reoperation were 40.54%（ P 〈 0. 01） and 32.43%（ P 〈 0. 01） respectively. No patients had permanent hypoparathyroidism and permanent recurrent laryngeal nerve injury. Conclusion Total thyroidectomy for Benign Thyroid Disease should be deserved to spread clinically. Because it can avoid reoperation for the recurrence and canceration caused by the remainder thyroid, it also can degrade the module of reoperation.But it is critical to operate finely.