米索前列醇预防产后出血临床观察

Clinical Observation on the Effect of Misoprostol Preventing Postpartum Hemorrhage

目的:探讨产妇舌下含服米索前列醇预防产后出血的效果.方法:实验组100例产妇于胎头着冠时舌下含服米索前列醇600μg,对照组90例产妇于胎肩娩出后立即静脉注射缩宫素20IU.用容积法和称重法测量两组产妇的产后出血量.结果:实验组产妇产后失血量平均为(116.43±94.32)ml,对照组产妇产后失血量平均为(296.52±79.41)ml,两组产妇产后失血量差异显著(P<0.01).结论:舌下含服米索前列醇可有效减少产妇的产后失血量.

Objective： To study the effect of misoprostol via sublingual administration to prevent postpartum hemorrhage. Methods： 100 parturients in test group were administrated sublingually with 600ug of misoprostol as soon as crowning of head, and 90 parturients in control group were injected 20IU of oxytocin via vein. The amount of postpartum hemorrhage was measured with volumetric and weighing methods. Results ：The average volume of bleeding for the parturients in test group was（116.43 ± 94.32） ml, and that for those in control group was （296.52 ± 79.41 ） ml. There was significant difference between the amount of bleeding in two groups（P 〈 0.01）. Conclusion ： Misoprostol via sublingual administration can effectively reduce the amount of postpartum hemorrhage.