亚绒盖乳菇化学成分的研究──Ⅰ.(22Z,24S)-啤酒甾醇的分离和鉴定

Studies on the Chemical Constituents of the Fruit Bodies of Yaronggairugu (Lactarius subvellereus)──Ⅰ. Isolation and Identification of (22Z, 24S)-Cerevisterol

从乳菇属真菌亚绒盖乳菇Lactariussubvellereus子实体的甲醇提取物中分得1个新化合物和7个已知化合物，经理化常数和光谱分析鉴定为（222，24S）-啤酒甾醇［（22Z，24S）－cerevis－terol，I），硬脂酸（stearicacid，Ⅱ），硬脂酸甲酯（methylstearate，Ⅲ），亚油酸（linoleicacid，Ⅳ），庚二酸（azelaicacid，V），牛蒡子素（arctigenin，Ⅵ），ergosta－7，22－dien－3－ol（Ⅶ），ergosta－7－en－3－ol（Ⅷ）。其中Ⅰ为新化合物，Ⅴ和Ⅵ为首次从该属真菌中得到。

From the methanolic extract of Lactarius subvellereus,one new and seven known compounds were isolated and identified as (22Z, 24S)-cerevisterol (Ⅰ),stearic acid(Ⅱ),methyl stearate (Ⅲ),linoleic acid (Ⅳ),azelaic acid (Ⅴ),arctigenin(Ⅵ),ergosta-7, 22-dien-3-ol (Ⅶ),and ergosta-7-en-3-ol (Ⅷ)by spectroscopic methods (CD,UV,IR,MS,1H,13CNMR) 。The new compound Ⅰand compound V and Ⅵ were obtained for the first time from the fungus Lactarius.