硝苯吡啶与氨酰心安对拔牙时心肌供血不全的防护作用比较

Comparison of Nefedipine and Atenolol in Preventing Myocardial Ischemia During tooth Extraction

本文观察了330例高血压合并冠心病患者(均经综合医院内科或心内科确诊)拔牙时心电图变化.共分为三组,每组110例,分别为含服硝苯吡啶10mg组,氨酰心安50mg组,及不服药的对照组.拔牙时心电图缺血性ST—T改变:在氨酰心安组有明显的改善作用,对室上性早搏也有减少作用;硝苯吡啶组对缺血性ST—T改变的改善作用不及氨酰心安,且对空上性早搏无减少作用.但氨酰心安组有三例出现P—R间期延长.

Objective: to compare the effect of Nefedipine and Atenolol in the prevention of myoeardial ischemia during tooh extraction.Materials and Methods; 330 patients suffering from hypertension complicated with coronary heart disease were divided into 3 groups. Patients in the first two groups were given Nefedipine or Atenolol preextraction, the 3rd was control group. ECG was used during the process of extraction.Results and Conclusions! the Atenolol is significantly better in the improvement of ST -T changes and reduction of superventricular premature complex as compared with Nefedipine.