体内外成熟卵子行单精子卵胞浆内注射助孕情况比较

Comparison of ICSI Outcome between in Vitro and in Vivo Maturation Oocytes

目的:比较体内外成熟卵子行单精子卵胞浆内注射的助孕效果。方法:体内、外成熟的卵子行单精子卵胞浆内注射(ICSI)后,对其受精和胚胎发育情况,以及临床结局进行比较。结果:体外成熟的卵子行ICSI受精率稍高于体内成熟卵(P<0.05),而获卵率、卵裂率则显著降低(P<0.05),胚胎退化率没有显著差别;两组临床妊娠率、种植率及流产率均无显著差别。结论:用体外成熟的卵子ICSI后助孕可取得与体内成熟卵子相似的结果。

Objective：To study the difference of ICSI outcome between in vitro and in vivo maturation oocytes. Methods：In this study,two groups of patients, oocytes maturated in vitro and in vivo, received ICSI and ET treatment, and their outcomes were compared. Results ：Oocytes maturated in vitro group, the patients had the higher rate of fertilization ,but the lower oocyte obtain and cleavage rate P〈0.05 ,while implantation,pregnant and abortion rate were similar to the in vivo group P〉0.05. Conclusions ：ICSI with oocytes maturated in vitro may have the similar outcome to with those maturated in vivo.