摘要
目的:研究新生儿缺氧缺血性脑病(hypoxicischemicencephalopathy,以下简称HIE)的发展规律及其预后情况。材料与方法:选择有围产期窒息史、头颅CT诊断为不同程度HIE的新生儿83例,分别于3个月、6个月、1岁、2岁和4岁以前进行头颅CT和临床复查。结果:3个月时56%病例有头颅CT异常,大部分表现为外部性脑积水,28%病例有神经系统的症状和体征。6个月时33%病例有CT异常,33%病例有临床表现。1岁以后约20%病例有CT异常,表现为局限性脑软化灶和脑萎缩,并有相应的临床表现。结论:(1)HIE所致脑质低密度灶在生后2~3个月内吸收消散。(2)HIE在3个月时有半数病例头颅CT表现异常,大部分表现为外部性脑积水,1岁以后,外部性脑积水愈合,约20%病例留有局限性脑软化和脑萎缩等严重后遗症。(3)HIE的预后与CT分度密切相关,轻度者预后良好,中、重度者预后差。
Purpose: To study the evolution of neonatal hypoxic ischemic encephalopathy (HIE). Materials and methods: Eighty three cases of asphyxial perinatal neonates were selected, and HIE was diagnosed on CT. Follow up study was carried out at the 3rd, 6th month, one and two years of age, and before four years old. Results: At 3rd month, 56% cases were abnormal on CT, mostly showing external hydrocephalus (HE). 28% cases had clinical manifestations of nervous system. At 6th month, 33% cases were abnormal on CT. 33% cases had clinical manifestations. After one year, about 20% cases had abnormal CT with localized cerebral softening and atrophy, and corresponding clinical manifestations. Conclusion: (1) Cerebral low density lesion was absorbed in 2 3 months; (2) At 3rd month, about half of the cases had abnormal CT, mainly HE. After one year, HE was recovered, and 20% cases had serious complications such as localized cerebral softening and atrophy. (3) Prognosis of HIE was closely related to the degree of abnormal manifestations on CT.
出处
《中华放射学杂志》
CAS
CSCD
北大核心
1997年第8期524-527,共4页
Chinese Journal of Radiology
基金
广东省卫生厅青年科学基金
关键词
新生儿
CT
缺氧缺血性脑病
随访
预后
Neonate Hypoxic encephalopathy Tomography, X ray computed