植物姜黄中姜黄素的超临界CO_2流体萃取工艺研究

Study on the extracting condition of curcumin in Curcuma longa by SFE

通过单因素实验和正交实验相结合的方法对超临界CO2流体萃取姜黄中姜黄素的工艺条件进行了研究,并采用HPLC法测定姜黄素含量,筛选出超临界CO2萃取姜黄素的最佳条件为:萃取压力25 MPa,萃取温度55℃,采用无水乙醇作为夹带剂,用量为35%,萃取时间为5 h,CO2流量3.5 L·min-1.该工艺条件稳定可行.

To optimize the conditions of supercritical fluid extraction（SFE） for curcumin in Curcuma longa, the preparation process of curcuma longa was studied by single factor level test and orthogonal tests. The extracts were analyzed by HPLC, The optimal extraction conditions for curcumin were pressure 25 MPa, temperature 55℃ , flow rate of CO2 3.5 L.min^-1 and adding co-solvent ethanol 35 % （mL.g-^1） to extract 5h, It is stable and feasible to extract curcumin by SFE.