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乳房Paget病1例 被引量:1

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摘要 患者女,48岁,右乳房红斑、糜烂、溃疡8年余,于2007年1月31日入院..8年前无明显诱因患者朽乳晕出现红斑,无明显瘙痒及疼痛,后红斑渐扩大,并出现糜烂、渗出、结痴,曾在外院按“湿疹”、“皮炎”等治疗(具体不详),可略好转,约半个月后糜烂、渗出再次反复出现。3年前局部出现溃疡,乳头时有血性溢液,并出现蚕蚀样变小及内陷。1年前右乳房增大,自扪及肿块.乳头消失,溃疡反复发生,红斑渐增大。
出处 《临床皮肤科杂志》 CAS CSCD 北大核心 2008年第1期44-45,共2页 Journal of Clinical Dermatology
关键词 PAGET病 乳房
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参考文献4

  • 1Asian F, Demirkesen C, Cagatay P, et al. Expression of eytokeratin subtypes in intraepidermal malignancies: a guide for differentiation[J]. J Cutan Pathol, 2006, 33(8): 531-538.
  • 2Kawase K, Dimaio DJ, Tucker SL, el ah Paget's disease of the breast: there is a role for breast-conserving therapy[J]. Ann Surg Oncol, 2005, 12(5): 391-397.
  • 3Mirer E, El Sayed F, Ammoury A, el al. Treatment of mammary and extramammary Paget's skirt disease with topical imiquimod [J]. J Dermatolog Treat, 2006, 17(3): 167-171.
  • 4Piekarski J, Jeziorski A, Baklinska M, et al. Patients with Paget disease of nipple and with palpable mass in breast have unfavorable prognosis[J]. J Exp Clin Cancer Res, 2004, 23(1): 33-37.

同被引文献7

  • 1Gabbi TV,Valente NY,Castro LG. Pigmented Paget's disease of the nipple mimicking cutaneous melanoma:importance of the immunohistochemical profile to differentiate between these diseases[J].Anais Brasileiros de Dermatologia,2006,(03):457-460.
  • 2Siponen E,Hukkinen K,Heikkil(o) P. Surgical treatment in Paget's disease of the breast[J].American Journal of Surgery,2010,(02):241-246.
  • 3Kawase K,Dimaio DJ,Tucker SL. Paget's disease of the breast:there is a role for breast-conserving therapy[J].Annals of Surgical Oncology,2005,(05):391-397.
  • 4Miter E,El Sayed F,Ammoury A. Treatment of mammary and extramammary Paget's skin disease with topical imiquimod[J].Journal of Dermatological Treatment,2006,(03):167-171.
  • 5Piekarski J,Jeziorski A,Baklinska M. Patients with Paget disease of nipple and with palpable mass in breast have unfavorable prognosis[J].Journal of Experimental & Clinical Cancer Research,2004,(01):33-37.
  • 6Lage D,Volpini Cde A,Sasseron Mda G. Paget's disease:the importance of the specialist[J].Anais Brasileiros de Dermatologia,2010,(03):365-369.
  • 7Silverstein MJ,Lagios MD,Groshen S. The influence of margin width on local control of ductal carcinoma in situ of the breast[J].New England Journal of Medicine,1999,(19):1455-1461.

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