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甘肃省汉族、回族和东乡族糖尿病患者血糖和血脂代谢异常的研究 被引量:2

Abnormal metabolism of blood glucose and blood-fat in diabetics of Han, Hui and Dongxiang ethnics in Gansu province
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摘要 研究显示许多糖尿病易感基因多态性与糖尿病及其并发症的发生有民族间的差异。笔者曾对甘肃回、汉两个民族2型糖尿病(2DM)、糖尿病肾病患者Apo-E的遗传多态性进行研究^[1],除了易感基因多态性存在明显的差异,2DM患者脂类代谢也存在明显的种族间差异^[2]。近年来2DM发病率升高趋势不仅表现在城镇和经济发达地区,
出处 《中华流行病学杂志》 CAS CSCD 北大核心 2008年第1期100-101,共2页 Chinese Journal of Epidemiology
基金 基金项目:甘肃省自然科学基金资助项目(3ys061a25-027)
关键词 糖尿病 血糖 血脂 代谢异常 民族 Diabetics Blood glucose Blood-fat Abnormalmetabolism Ethnics
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  • 1向伟,马燕琳,符生苗,陈炽,杨进福,赵水平,郭德兴,赵迪成,聂赛,王福利.单纯性肥胖儿童脂肪细胞载脂蛋白E基因的表达[J].中华内分泌代谢杂志,2005,21(2):143-144. 被引量:3
  • 2罗俊,心血管病学进展,1992年,13卷,105页
  • 3Rogus JJ, Moczulski D, Freire MBS, et al. Diabetic nephropathy is associated with AGT polymorphism T235: results of a family-based study. Hypertension, 1998,31:627-631.
  • 4de Azevedo MJ, Dalmaz CA, Caramori ML, et al. ACE and PC-1 gene polymorphisms in normoalbuminufic type 1 diabetic patients: a 10-year prospective study. J Diabetes Complications, 2002,16:255-262.
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  • 6Shpichinesky V, Raz I, Friedlander Y, et al. The association between two common mutations C677T and A1298C in human methylene-tetrahydrofolate reductase gene and the risk for diabetic nephropathy in type Ⅱ diabetic patients. J Nutr, 2000,130:2493-2497.
  • 7Uusitupa M, Sarkkinen E, Kervinen K, et al. Apolipoprotein E phenotype and blood pressure. Lancet, 1994,343:57.
  • 8Bennouar N, Allami A, Laraqui A, et al. Apolipoprotein E and angiotensin-converting enzyme gene polymorphisms as risk factors of coronary disease. Ann Biol Clin (Paris), 2004,62:295-304.
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  • 10Eto M, Saito M, Okada M, et al. Apolipoprotein E genetic polymorphism, remnant lipoproteins, and nephropathy in type 2 diabetic patients. Am J Kidney Dis, 2002,40:243-251.

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