2-羟基-3-氯丙基丙烯酸酯的合成分析

Analysis on Synthesis of 2-Hydroxyl-3-Chloropropyl Acrylate

以丙烯酸（AA）与环氧氯丙烷（ECH）开环酯化合成2-羟-3-氯丙基丙烯酸酯。研究分析不同金属有机络合物以及相关因素对合成的影响。合成的适宜条件为：反应温度90℃，环烷酸铁为催化剂，占反应物总重量的1％；n（环氧氯丙烷）：n（丙烯酸）=1．2，酸转化率98％；产物在316Pa，89～91．5℃时减压蒸馏，收率94．7％。

The 2-hydroxyl-3-chloropropyl acrylate is synthesized by the ring-opening esterifying reaction of epichlorohydrin （ECH） and acrylic acid （AA） with a catalyst-active complex compound. Different metal complex compound and the related factors affecting reaction were researched. The condition of synthesis is： reaction in 90℃, activator with iron（ Ⅲ ） naphthenate 1% by wt, n （epichlorohydrin） ： n （acrylic acid） = 1.2, responsive matter of mol proportion 1.2, then removed the object we needed in vacua, under 319 Pa at 89-91.5℃ to the title compound in 94.7% yield.