摘要
综述了血氧饱和度无损测量的方法,泰勒级数法、近红外光谱法、氧指数(IOX)法以及基于蒙特卡罗的多元线性回归法等,分析了这些方法的优缺点。基于光动力疗法治疗机制(PDT),提出了一种修正的氧指数法,初步分析表明该法能够监测光动力疗法治疗鲜红斑痣(PWS)过程中血氧饱和度变化情况。
The noninvasive methods for measuring blood oxygen saturation were reviewed, including tayor series expansion model, near infrared spectroscopy,oxygenation index (IOX) and multiple regression analysis aided by monte carlo simulation. Moreover the advantages and disadvantages of each method were discussed. Based on the mechanism of photodynamic therapy (PDT), a modified IOX method was developed, and the preliminary result indicates this method could monitor the changes of blood oxygen saturation in process of PDT treatment for port wine stain (PWS).
出处
《激光与光电子学进展》
CSCD
北大核心
2008年第1期24-28,共5页
Laser & Optoelectronics Progress
基金
国家自然科学基金(60711120031)
福建省项目(2005I009
2005,847
JA04168)
医学光电科学与技术教育部重点实验室项目(JYG0506)
关键词
医用光学与生物技术
血氧饱和度
无损测量
光谱法
鲜红斑痣
光动力疗法
medical optics and biotechnology
blood oxygen saturation
non-invasive measurement
spectroscopy
port wine stain
photodynamic therapy