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氩氦消融联合乙酸注射治疗48例肝癌

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摘要 目的联合经皮局部氩氦冷冻治疗(percutaneous local cryotherapy,PLCT)和经皮瘤内乙酸注射(percutaneous acetic acid injection therapy,PAIT)两种方法治疗失去手术机会的肝癌,观察其疗效和安全性。方法48例肝癌患者分为3组,14例患者32个病灶施行PLCT,17例患者35个病灶施行PAIT,17例患者39个病灶施行PLCT联合PAIT治疗。结果单纯PLCT治疗的肿瘤大小50%以上缩小率为59.4%(19/32);单纯PAIT治疗的肿瘤50%以上缩小率为48.6%(17/35);PLCT联合PAIT治疗的肿瘤50%以上缩小率为87.2%(34/39)。单纯PLCT治疗后1年生存率为61.5%(8/13)、单纯PAIT治疗后为47.1%(8/17)、PLCT联合PAIT治疗后为82.4%(14/17)。各组患者AFP水平治疗后有不同程度下降。结论PLCT联合PAIT治疗其效果优于单纯PLCT或单纯的PAIT治疗。
出处 《广东医学》 CAS CSCD 北大核心 2008年第1期142-144,共3页 Guangdong Medical Journal
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