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结核疫苗相关研究现状与展望 被引量：3

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作者 马爱丽 曹以诚
机构地区 华南理工大学生物科学与工程学院
出处 《广东医学》 CAS CSCD 北大核心 2008年第1期147-149,共3页 Guangdong Medical Journal
基金 国家自然科学基金重大研究计划项目(编号:90412015) 华南理工大学高水平大学建设重大项目(编号:321-D75010)
关键词 结核疫苗 耐药性结核病 分子生物学技术 重组BCG疫苗 免疫保护效果 候选疫苗 DNA疫苗 免疫保护力
分类号 R52 [医药卫生—内科学]
  • 相关文献

参考文献25

  • 1RUSSELL D G.Highlighting the parallels between human and bovine tuberculosis[J].J Vet Med Educ,2003,30:140 -142.
  • 2CHAN J,FLYNN J.The immunological aspects of latency in tuberculosis[J].Clin Immunol,2004,110 (1):2-12.
  • 3RIBEIRO RODRIGUES R,RESENDE CO T,ROJAS R,et al.A role for CD4^ + CD25 ^+ T cells in regulation of the immune response during human tuberculosis[J].Clin Exp Immunol,2006,144:25-34.
  • 4ROOK G A,DHEDA K,ZUMLA A.Immune responses to tuberculosis in developing countries:implications for new vaccines[J].Nat Rev Immmunol,2005,5:661 -667.
  • 5DEMISSIE A,ABEBE M,ASEFFA A,et al.Healthy individuals that control a latent infection with mycobacterium tuberculosis express high levels of Th1 cytokines and the IL-4 antagonist IL-4 delta 2[J].J Immunol,2004,172:6 938 -6 943.
  • 6LANGRISH C L,CHEN Y,BLUMENSCHEIN W M,et al.IL-23 drives a pathogenic T cell population that induces autoimmune inflammation[J].J Exp Med,2005,201:233-240.
  • 7HAPPEL K I,LOCKHART E A,MASON C M,et al.Pulmonary interleukin -23 gene delivery increases local T-cell immunity and controls growth of Mycobacterium tuberculosis in the lungs[J].Infect Immun,2005,73:5 782-5 788.
  • 8BASARABA R J,IZZO A A,BRANDT L,et al.Decreased survival of guinea pigs infected with Mycobacterium tuberculosis after multiple BCG vaccinations[J].Vaccine,2006,24:280-286.
  • 9SKEIKY Y A,ALDERSON M R,OVENDALE P J,et al.Differential immune responses and protective efficacy induced by components of a tuberculosis polyprotein vaccine,Mtb72F,delivered as naked DNA or recombinant protein[J].J Immunol,2004,172(12):7 618 -7 628.
  • 10LANGERMANS J A,DOHERTY T M,VERVENNE R A,et al.Protection of macaques against Mycobacterium tuberculosis infection by a subunit vaccine based on a fusion protein of antigen 85B and ESAT-6[J].Vaccine,2005,23(21):2 740-2 750.

二级参考文献42

  • 1李晖,任小华,钟森,任红.结核分枝杆菌mtb8.4/hIL12嵌合基因的克隆及真核表达质粒的构建[J].重庆医科大学学报,2004,29(5):576-579. 被引量：1
  • 2张海,师长宏,薛莹,姜泓,高雪,柏银兰,王丽梅,徐志凯.结核分枝杆菌esat6-cfp10融合基因疫苗的构建及表达[J].第四军医大学学报,2005,26(3):193-195. 被引量：4
  • 3胡贵方,孙莉莎,金宏,欧程山,蒋毅萍,庞建新.含hTERT片段的重组逆转录病毒感染对树突状细胞功能的影响[J].南方医科大学学报,2006,26(4):394-397. 被引量：2
  • 4Britton WJ, Palendira U. Improving vaccines against tuberculosis [J]. Immunol Cell Biol, 2003, 81(1): 34-45.
  • 5Delogu G, Howard A, Collins FM, et al. DNA vaccination against Tuberculosis: expression of a Ubiquitin-conjugated tuberculosis protein enhances antimycobacterial immunity [ J ].Infect Immun, 2000, 68 (6) : 3 097 - 3 102.
  • 6Morris S, Kelley C, Howard A, et al. The immunogenicity of single and combination DNA vaccines against tuberculosis[J].Vaccine, 2000, 18 (20): 2 155- 2 163.
  • 7Tanghe A, D'souza S, Rosseels V, et al. Improved immunogenicity and protective efficacy of a tuberculosis DNA vaccine encoding Ag85 by protein boosting[J]. Infect Immun,2001, 69 (5) : 3 041 - 3 047.
  • 8Delogu G, Brennan MJ. Comparative immune response to PE and PE-PGRS antigens of Mycobacterium tuberculosis [ J ].Infect Immun, 2001, 69 (9): 5 606-5 611.
  • 9Coler RN, Skeiky YA, Vedvick T, et al. Molecular cloning and immunologic reactivity of a novel low molecular mass antigen of Mycobaclerium tuberculosis [ J]. J Immunol, 1998,161 (5): 2356-2364.
  • 10Coler RN, Campos Neto A, Ovendale P, et al. Vaccinalion with the T cell antigen Mtb8.4 protects against challenge with Mycobacterium tuberculosis [ J ]. J Immunol, 2001,166 (10): 6227-6 235.

共引文献17

同被引文献92

引证文献3

二级引证文献15

广东医学
2008年 第1期

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