我院150例药品不良反应报告分析

Adverse Drug Reaction Reports:Analysis of 150 Cases in Our Hospital

目的:了解我院药品不良反应(ADR)发生的特点并评价ADR报告质量,促进临床合理用药,提高ADR监测工作质量。方法:收集到我院2005～2006年上报的ADR病例150例,并应用Excel软件对性别、年龄、涉及的药品种类、涉及的器官或系统及临床表现、ADR报告质量等进行分类统计。结果:由抗微生物药引起的ADR所占比例最高,ADR损害的器官或系统以皮肤及其附件最为常见,ADR上报率偏低,报告质量需提高。结论:应进一步加强我院ADR的监测和宣传工作,提高专业人员责任意识,减少ADR发生。

OBJECTIVE：To investigate the occurrence features of adverse drug reactions（ADR） and evaluate the quality of ADR reports in our hospital in order to promote clinic rational drug use and improve the quality of ADR monitoring.METHODS： A total of 150 ADR cases collected in our hospital during 2005-2006 were analyzed in respect of ADR patients＇ age and sex,drug kinds,ADR- involved organs or systems and clinical manifestations, ADR report quality etc using Excel.RESULTS： The ADR were predominantly induced by antimicrobial drugs and characterized by the damage of skin and its appendants.The ADR reporting rate was on the low side and the reporting quantity remained to be enhanced.CONCLUSION ：ADR monitoring and publicizing should be further reinforced and professional staff＇ s responsibility awareness remains to be improved to lessen ADR incidence.