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DBD等离子体制备类-PEO生物功能薄膜及其生物相容性研究 被引量:1

Study of DBD Plasma Polymerization PEO-like Functional Coatings and its Biocompatibility Properties
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摘要 研究了介质阻挡放电(DBD)的功率、气压、极板间距以及电源频率等放电参数对沉积类-PEO功能薄膜化学结构以及表面性能的影响;同时采用体外细胞培养的方法,研究了类-PEO功能薄膜对富血血小板以及细胞的吸附,通过倒置显微镜观察细胞黏附的形态变化。结论:DBD等离子体能在较高的气压条件下聚合结构性能优异的类-PEO生物功能薄膜,所制备的类-PEO生物功能薄膜能有效的减少富血血小板的吸附,对蛋白质表现出较好的抗吸附性能。 The influence of plasma parameters such as discharge power, work pressure, and electrode gap as well as discharge frequency on the chemical component, surface properties and biocompatibility of the PEO-like coating were studied by water contact angle ( WCA) measurement, Fourier-transform infrared spectroscopy ( FT IR), X-ray photoelectron spectroscopy ( XPS), and atomic force microscopy ( AFM ). In vitro cell culture and the adsorption the blood platelet were also carried out, which the cell adsorption and morphology were acquired with a phase contrast microscope. The results showed that DBD plasma can polymerize an excellent PEO-like coating, and coatings can effectively reduce the adsorption of blood platelet and prevent protein adhesion.
出处 《包装工程》 CAS CSCD 北大核心 2008年第1期4-6,共3页 Packaging Engineering
基金 国家自然科学基金资助项目(10475010) 北京市重点实验室开放课题资助(kf060201)
关键词 介质阻挡放电 类-PEO 功能薄膜 细胞吸附 生物相容性 dielectric barrier discharge ( DBD ) PEO-like functional coating cell adhesion
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参考文献11

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