保定市18岁及以上人群心境恶劣流行病学调查

Epidemiologic investigation of dysthymia in the people aged 18 and older in Baoding city

目的：了解保定市18岁及以上人群心境恶劣的时点患病率和分布特点。方法：2004年10月至2005年3月采用多阶段分层整群抽样方法随机抽取10073名≥18岁的人群为调查对象，用扩展的一般健康问卷（GHQ-12）将凋查对象分为高、中、低危险组，以美国精神障碍诊断标准（DSM-Ⅳ）对调查对象进行DSM—Ⅳ—TR轴Ⅰ障碍定式临床检查（SCID），对心境恶劣进行诊断。结果：9021人完成调查，心境恶劣时点患病率为2．15％（95％ CI为1．85％-2．45％），女性显著高于男性（2．71％，1．62％），农村高于城市（2．30％，1．01％）。结论：心境恶劣具有高发倾向，明显损害患营社会功能、是需要迫切关注的公共卫生问题。

Objective：To describe the current prevalence and distribution of all types of dysthymia in Baoding city. Methods： From Oct. 2004 to Mar. 2005, Stratified multi -stage cluster randomization was used to identify 10073 subjects≥ 18 years of age in Baoding city. An expanded version of the General Health Questionnaire （ GHQ - 12） was used to identify subgroups of subjects at high, moderate and low risk of having a mental disorder, then psychiatrists determined their diagnoses by administering a structured psychiatric examination （SCID） that employs American diagnostic criteria for mental disorders （DSM - IV）. Results： 9021 subjects completed the screening, The overall current rate of dysthymia was 2.15% （95% CI = 1.85% - 2. 45% ） o The overall prevalence of dysthymia was obviously higher in women than in men （2.71% , 1.62% ） ,and higher in rural than in urban areas（2.30% , 1.01% ）. Conclusions： Dysthymia, impairing social function, have a higher trend of prevalence and important implications to public health issue,