彩色多普勒超声对移植肾慢性排斥反应诊断的研究

Research on Color Doppler Ultrasonography to Chronic Rejection Response Diagnosis of Kidney Transplant

目的探讨彩色多普勒超声对移植肾慢性排斥反应的诊断价值。方法对98例肾移植患者行彩色多普勒超声检查,其中移植肾慢性排斥反应组(排斥组)66例,肾移植术后正常组32例,测量两组移植肾的最大血流速度(Vmax)、搏动指数(PI)、阻力指数(RI),分析搏动指数与血肌酐(Scr)的关系。结果排斥组与正常组的Vmax分别为(20±7)cm/s、(23±5)cm/s,P<O.05;排斥组与正常组的阻力指数分别为l.25±0.21、0.67±0.13,P<0.01;搏动指数分别为1.65±0.63、0.75±0.11,P<0.01;随着阻力指数增大对慢性排斥反应诊断敏感性下降,而特异性上升;血肌酐随阻力指数增大而升高。结论彩色多普勒超声检查能反映移植肾的血流信息及其与肾功能的关系,有助于移植肾慢性排斥反应的诊断。

Objective： To evaluate color Doppler ultrasound on chronic renal allograft rejection of diagnostic value. Method ： 98 cases of renal transplant patients with Color Doppler Ultrasonography, with chronic renal transplant rejection to 66, after kidney transplantation normal group of 32 patients, measurement of renal transplantation were the biggest velocity （Vmax）, pulsatility index （PI）, resistance index （RI）, analysizing pulsatility index and serum creatinine （SCr） relationship. Results ： exclusive group with the normal group, the Vmax of （20 ± 7） s, （23 ± 5） s, P〈0.05; exclusive group and the normal group of resistance index were 1.25 ± 0.21, 0.67 ± 0.13, P〈0.01; pulsatility index were： 1.65 ± 0.63, 0.75 ± 0.11, P 〈0.01 with the index increasing resistance to the diagnosis of chronic rejection sensitivity, and the specificity increased; serum creatinine with the resistive index is increased. Conclusion： Color Doppler ultrasonography can reflect renal transplantation, the information flow and renal function, and contribute to chronic renal allograft rejection diagnosis.