摘要
本项研究选用三种化学结构相似，致癌／致灾变强度不同的苯胺衍生物处理BARB／C小鼠，然后对其进行免疫学检测。结果显示，随着化学物致癌／致突变性的增强，对机体体液免疫和非特异性免疫功能的抑制作用增强，并有明显的剂量-反应关系。
The effect of three aniline derivatives with similar structure and different carcinogenic/mutagenic potency on immunologic function of BARB/C mice was investigated. The results suggested that the inhibitive effect on the humoral immunity and non-specific immunologic function increased as the carci nogenic /mutagenic potent ial of the che micals increases. Meanwhile, there existed a clear dose-response relationship.
出处
《工业卫生与职业病》
CAS
CSCD
1997年第1期7-9,共3页
Industrial Health and Occupational Diseases
关键词
苯胺衍生物
免疫功能
Aniline derivative
Immunologic function
