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神经干细胞定向迁移机制研究新进展 被引量:3

New progress in research of the mechanism of directional migration of neural stem cells
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摘要 二十世纪九十年代初期,研究者从成年哺乳动物脑组织内分离出能够不断分裂增殖,具有多分化潜能的细胞群落,提出了神经干细胞(neural stem cells,NSCs)的概念。近年来的研究发现,在哺乳动物胚胎发育过程或病理情况下NSCs存在有序的定向迁移过程。NSCs的定向迁移不仅对机体发育具有至关重要的作用,对于中枢神经系统损伤的修复也具有重大意义。在迁移过程中NSCs是如何循着一定的路线,确定路标,顺利到达目的地一直是人们感兴趣的问题。本文就近年来在NSCs定向迁移机制研究中取得的一些进展做一综述。
出处 《中华神经医学杂志》 CAS CSCD 2008年第1期99-101,共3页 Chinese Journal of Neuromedicine
基金 上海市教委自然科学基金(04BB23) 上海市教委自然科学重点项目(07ZZ42)
关键词 神经干细胞 细胞迁移 Neural stem cells Cell migration
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