摘要
目的:研究羌银解热合剂的抗炎镇痛、解热作用。方法:以羌银解热合剂高剂量组(25.2g/kg)、中剂量组(12.6g/kg)、低剂量组(6.3g/kg)灌胃,分别观察对酵母混悬液致大鼠发热的解热作用,对鸡蛋清致大鼠足跖肿胀和二甲苯致小鼠耳肿胀的抗炎作用,对小鼠热板法和冰醋酸致小鼠扭体的镇痛作用。结果:羌银解热合剂高剂量组能显著抑制酵母混悬液致大鼠发热、鸡蛋清致大鼠足跖肿胀、二甲苯致小鼠耳肿胀,显著提高小鼠热板法的痛阈值,显著减少冰醋酸致小鼠扭体次数。结论:羌银解热合剂具有较好的解热、抗炎、镇痛作用。
Objective ： To investigate the anti -inflammatory analgesic and anti -febrile effects of Qiangyin Jiere Mixture（QYM）. Methods ： The ebrile model of rats was induced by injecting fresh yeast subcutaneously. The acute ear edema model of mice was induced with dimethylbenzene. The foot edema model of rats was induced with egg white. The pain models were established by acetic acid and hot plate in mice. Results ：QYM depressed the fervescence by yeast effectively in rats, inhibited foot edema in rats and ear swelling in mice and inhibited the pain evidently caused by acetic acid and hot plate in mice. Conclusion ： QYM has obvious antiinflammatory, analgesic and antifebric effect.
出处
《中华中医药学刊》
CAS
2008年第1期91-93,共3页
Chinese Archives of Traditional Chinese Medicine
基金
广东省中医药局科技基金资助项目(2005105182)
关键词
羌银解热合剂
解热
抗炎
镇痛
Qiangyin Jiere mixture
anti - inflammatory
anti - febric
analgesic
