FK506(Tacrolimus)治疗激素依赖性重症肌无力的研究进展
摘要
重症肌无力是一种由T细胞依赖的、抗体介导的自身免疫性疾病。FK506是一种大环内脂类的代谢物,具有选择性抑制辅助性T细胞活动的特性。此文就FK506抑制T细胞的作用机制、药代动力学机制、在实验性自身免疫性重症肌无力中的研究情况、临床治疗方面的证据以及不良反应进行了综述。
出处
《中国神经免疫学和神经病学杂志》
CAS
2008年第1期63-65,共3页
Chinese Journal of Neuroimmunology and Neurology
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