期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

大肠癌组织畸胎瘤衍生生长因子1蛋白表达及临床意义 被引量：15

原文传递
导出
摘要 畸胎瘤衍生生长因子1（teratocarcinoma-derived growth factor-1，TDGF1）基因是表皮生长因子家族重要成员之一。研究发现，TDGF1基因在许多实体瘤中过度表达，而正常组织表达极低或者不表达。TDGF1基因与某些肿瘤如乳腺癌侵袭有关。但国内目前尚无此项研究，也不清楚TDGF1基因与大肠癌细胞侵袭转移的关系。本研究采用免疫组化方法，
作者 范钰 张尤历 吴莺 张宇川 王崇强 郑树
机构地区 江苏大学附属医院消化科 浙江大学肿瘤研究所
出处 《中华消化内镜杂志》 2007年第6期442-443,共2页 Chinese Journal of Digestive Endoscopy
基金 中国博士后基金(2003033547) 镇江市科技计划项目(SH2006019)
关键词 畸胎瘤 生长因子1 大肠癌组织 临床意义 蛋白表达 F1基因 衍生生长因子 生长因子家族
分类号 R735.34 [医药卫生—肿瘤]
  • 相关文献

参考文献9

  • 1Ciccodicola A, Dono R, Obici S, et al. Molecular characterization of a gene of the ‘EGF family' expressed in undifferentiated human NTERA2 teratocarcinoma cells. EMBO J, 1989,8 : 1987-1991.
  • 2Ciardiello F, Kim N, Saeki T, et al. Differential expression of epidermal growth factor-related proteins in human colorectal tumors. Proc Natl Acad Sci USA,1991,88: 7792-7796.
  • 3Friess H, Yamanaka Y, Buchler M,et al. Cfipto, a member of the epidermal growth factor family, is over-expressed in human pancreatic cancer and chronic pancreatitis. Int J Cancer, 1994,56: 668-674.
  • 4Panico L, D'Antonio A, Salvatore G, et al. Differential immunohisto-chemical detection of transforming growth factor alpha, amphiregulin and CRIPTO in human normal and malignant breast tissues. Int J Cancer, 1996, 65 : 51-56.
  • 5Fontanini G, De Laurentiis M, Vignati S, et al. Evaluation of epidermal growth factor-related growth factors and receptors and of neoangiogenesis in completely reseeted stage I-IIIA non-small-cell lung cancer: amphiragulin and mierovessel count are independent prognostic indicators of survival. Clin Cancer Res, 1998,4: 241-249.
  • 6D'Antonio A, Losito S, Pignata S, et al. Transforming growth factor alpha, amphiregulin and cripto-1 are frequently expressed in advanced human ovarian carcinomas. Int J Oncol, 2002, 21 : 941-948.
  • 7Ertoy D, Ayhan A, Sarac E, et al. Clinicopathological implication of cripto expression in early stage invasive cervical carcinomas. Eur J Cancer,2000,36 : 1002-1007.
  • 8Normanno N, De Luca A, Bianco C, et al. Cripto-1 overexpression leads to enhanced invasiveness and resistance to anoikis in human MCF-7 breast cancer cells. J Cell Physiol,2004 ,198 :31-39.
  • 9范钰,郑树,丁佳逸.脂质体介导的cripto反义寡核苷酸抑制结肠癌细胞端粒酶活性[J].中国病理生理杂志,2006,22(4):762-765. 被引量：42

二级参考文献15

  • 1张海伟,罗英儒,郑佩娥,文剑明.蛋白激酶C的活性变化对人肝癌细胞增殖及端粒酶表达的影响[J].中国病理生理杂志,2004,20(7):1176-1178. 被引量：3
  • 2Adamson ED,Minchiotti G,Salomon DS.Cripto:a tumor growth factor and more[J].J Cell Physiol,2002,190(3):267-278.
  • 3Ciardiello F,Kim N,Saeki T,et al.Differential expression of epidermal growth factor-related proteins in human colorectal tumors[J].Proc Natl Acad Sci USA,1991,88(17):7792 -7796.
  • 4Normanno N,De Luca A,Salomon DS,et al.Epidermal growth factor-related peptides as targets for experimental therapy of human colon carcinoma[J].Cancer Detect Prey,1998,22(1):62-67.
  • 5De Angelis E,Grassi M,Gullick WJ,et al.Expression of cripto and amphiregulin in colon mucosa from high risk colon cancer families[J].Int J Oncol,1999,14(3):437-440.
  • 6Baldassarre G,Tucci M,Lembo G,et al.A truncated form of teratocarcinoma-derived growth factor-1 (cripto-1) mRNA expressed in human colon carcinoma cell lines and tumors[J].Tumour Biol,2001,22(5):286-293.
  • 7Tang R,Cheng AJ,Wang JY,et al.Close correlation between telomerase expression and adenomatous polyp progression in multistep colorectal carcinogenesis[ J ].Cancer Res,1998,58(18):4052-4054.
  • 8Engelhardt M,Drullinsky P,Guillem J,et al.Telomerase and telomere length in the development and progression of premalignant lesions to colorectal cancer[J].Clin Cancer Res,1997,3(11):1931-1941.
  • 9Mizumoto I,Ogawa Y,Niiyama H,et al.Possible role of telomerase activation in the multistep tumor progression of periampullary lesions in patients with familial adenomatous polyposis[J].Am J Gastroenterol,2001,96(4):1261-1265.
  • 10Boldrini L,Faviana P,Gisfredi S,et al.Evaluation of telomerase in the development and progression of colon cancer[J].Int J Mol Med,2002,10(5):589-592.

共引文献41

同被引文献116

引证文献15

二级引证文献21

中华消化内镜杂志
2007年 第6期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部