癌症相对生存率的回归模型分析

Regression Analysis of Relative Survival Rate of Cancer.

癌症病人的生存情况常用相对生存率指标进行描述。相对生存率定义为病人群体的观察生存率与假定其为一般人群时的期望生存率之比，并要求病人群体与一般人群在随访期初除肿瘤之外影响他们生存的因素（如年龄、性别、民族、年代等）相同。本文就比例危险回归模型如何应用于癌症相对生存率的分析加以探讨。并借助于统计软件ＧＬＩＭ，详细说明肺癌相对生存率回归模型分析的应用。样本资料为１９８４～１９８６年在上海市区诊断的肺癌新病例５年随访生存资料。

Survival experience of cancer is often measured using the relative survival rate. The rate is defined as the ratio of the observed survival rate in the patient group under study to the expected survival rate in a group of people similar to the patient group at the beginning of the follow up interval,with respect to all possible factors (e.g.age、sex、calendar year、race and etc.)affecting survival,except the cancer in question.This paper explores how a proportional hazards regression model may be adapted to the relative survival rates by using software of GLIM. We use the example to illustrate its application in detail,the data was from a follow up study of lung cancer patients which were diagnosed in Shanghai urban in 1984 1986.