不同品种的升麻蜜制前后药理活性的比较

Comparison of Activities of Various Species of Rhizoma Cimicifugae and Their Honey Processed Products

目的:比较不同品种升麻蜜制前后镇痛和镇静活性的差异。方法:采用小鼠福尔马林致痛反应、热板法、醋酸扭体实验和小鼠自发活动及举双肢法观察升麻和兴安升麻生药和蜜制品的镇痛和镇静活性。结果:升麻和兴安升麻蜜制品的镇痛和镇静活性均明显强于各自的生药。结论:不同品种升麻其镇痛和镇静活性经过蜜制后显著增强。

Objective ： To compare the analgesic and sedative effects of various species of Rhizoma Cimicifugae and their processed products with honey. Methods： The three kinds of analgesic experiments of formalin, hot plate and writhing tests, and the number of spontaneous activities and raise forelimbs were adopted in mice. Results： All samples showed antinociceptive activities in the two pha- ses of formalin, tail immersion and writhing tests and sedative properties in the spontaneous locomotor activity test. The analgesic and sedative effects of processed Rhizoma Cimicifugae were higher than crude drugs. Conclusion： The present results demonstrate that the antinociceptive and sedative activity of samples processed with honey are more potent than crude drugs.