恶性肿瘤脑转移的治疗及预后分析

An analysis of the prognostic factors and treatment result for malignant tumours with brain metastasis

本文对90例恶性肿瘤脑转移的治疗及预后进行了总结，结果显示：手术＋放疗＋化疗，手术＋放疗，放疗＋化疗的中位生存期分别为10．5个月、9．7个月及8个月，1年生存率分别为40％、40％及30．43％，显著优于单纯手术组，单纯放疗组及单纯化疗组（P＜0．05）。卡氏评分≥60分，原发灶控制、仅有颅内转移的患者预后较好。作者认为在恶性肿瘤脑转移治疗中，以放疗为主的综合治疗是一种比较合理的治疗方法，对延长生存期有不同程度的提高。

To analyze the treatment result and Pragnostic factors for ninety cases of patients with brain matastasis. The median survival period were 10. 5 months in surgerg plus radiotherapy and chemotherapy group, 9. 7 months in surgerg plus radiotherapy 8 months in radiotherapy combined with chemotherapy. And one year survival rate were 40%、40%、30. 43%in three groups. The result were much better than that in surgery. radiotherapy or chemotherapy along (P<0. 05). The patients of KPS≥60. primary tumours were controlled and no metastasis in other organs may have a better prognosis. Combination therapy of radiotherapy plus other therapys is a better treatment wethod for brain metastasis. It can proloned the survival period of the patient with brain metastasis.