核酸与药物分子相互作用模式及研究进展

The Interaction Mode between the Nucleic Acid and the Medicine Molecules and the Research Progress

介绍了核酸与药物分子相互作用模式,并围绕药物小分子与核酸相互作用的模式-非共价作用、共价作用、剪切作用,探讨了对这种作用模式进行研究的方法进展。提出了综合应用多种分析方法进行研究药物分子和核酸的作用模式。

This paper summarized the interaction mode between the nucleic acid and the medicine molecules. And it studyed the research progress about the mode - noncovalence effect, covalence effect,cutting effect. It brought forward that it shoiyld used several analytical methods to study the interaction mode between the nucleic acid and the medicine molecules.