小儿巨大肾母细胞瘤的术前栓塞化疗

Preoperative chemoembolization of huge nephroblastoma in children

对5例小儿（1～5岁）巨大肾母细胞瘤行选择性血管造影，井行术前栓塞化疗、肿瘤下界均超过髂前上棘水平，内界超过腹中线，1例并伴广泛肺转移。本文介绍肾母细胞瘤栓塞化疗的指征和方法。栓塞化疗可使药物直接作用于肿瘤病灶，剂量小，副作用少，效果明显，可将术前化疗时间缩短至2周左右，手术时出血少，易完整切除，但可出现临床分期的“降期”现象。

Selected angiography and chemoembolization were applied in 5 cases of nephroblastoma aged 1 to 5 years. The indication,materials and method of chemoembolization were introduced. The advantages of chemoembolization are:direct local chemotherapy, smaller dosage, less complication with more effect;the duration of preoperative therapy reduced to 2 weeks; bleeding is less and radical extirpation is easier during the operation.The disadvantage is 'downstaging' of tumor.