不明原因感音神经性聋患者红细胞免疫功能检测

Preliminary study on erythrocyte immunity during sensorineural hearing loss of unknown etiology

为探讨不明原因感音神经性聋患者红细胞免疫功能，采用酵母菌花环试验对５０例不明原因感音神经性聋患者红细胞免疫功能进行检测，并与正常组进行比较，结果显示：不明原因感音神经性聋患者红细胞Ｇ３ｂ受体（ＲＢＣ－Ｃ３ｂＲ）花环率降低，红细胞免疫复合物（ＲＢＣ－ＩＣ）花环率升高，且皆与正常组有显著性差异，提示不明原因的感音神经性聋患者有继发性红细胞免疫功能低下，可能与红细胞免疫调节功能紊乱有关。

Red cell immune function was determined in 50 patients with sensorineural deafness and 30 healthy persons as control. The results showed that in patients with sensorineural deafness, the red cell C 3b receptor (RBC C 3b R) rosette formation rate (15.10±1.66) was lowered markedly than controls (18.95±1.16, P <0.001) and the red cell surface immune complex (RBC IC 9.94±1.68) was elevated markedly than controls (7.44±1.17, P <0.001). The results indicate that the red cell immunity in the patients with sensorineural deafness of unknown etiology is lowered.