血浆清蛋白胆碱酯酶及前白蛋白检测在肝病诊治中的临床意义

Significance of Determinating Plasma-albumin,Cholinesteras and Prealbumin in the Hepatopathy

目的:通过测定血浆清蛋白(A lb)、胆碱酯酶(Che)、及前白蛋白(PA)的水平变化,用于了解各种肝病的性质、转归和判断预后。方法:血浆清蛋白(A lb)为终点法、胆碱酯酶(Che)为酶动力学法、及前白蛋白(PA)免疫投射比浊法。结果:急性病毒性肝炎中A lb降低并不明显,而Che、PA降低明显,在其他各型病毒性肝炎中A lb、Che、PA浓度均明显减低,显著低于健康对照组,且三者呈正相关。结论:血浆Che、PA比白蛋白能更早更敏感的反映肝脏合成功能的损伤、恢复程度,三者联合检测对病毒性肝炎的分型鉴别、预后、用药的疗效有着重要的临床意义。

Objective： To measure the levels of plasma - albumin （ Alb）, cholinesterase （Che） and prealbumin（ PA ） in investigating the quality, change and judgement of prognosis in various hepatic diseases. Method： AIb, Che and PA were examined by end - point method, enzyme kinetics and immunologic projective turbidimetry method respectively. Result： Alb was no significantly lower, while Che and PA were significantly lower in acute virus hepatitis. In the other various virus hepatitis, Alb, Che and PA were significantly lower than those of healthy groups, which had positive correlation. Conclusion： Che and PA reflect lesion recoverable degree of liver function more sensitively and earlier than that of Alb. It suggest that combining three kinds of methods is pracitical value for anticipating the differentiating types, prognosis and effect in virus hepatitis.