自身免疫性大疱性皮肤病四例诊断与治疗评析
被引量:1
摘要
病例1 患者男,44岁。因全身红斑水疱5个月,加重1个月,于2007年7月27日入院。查体:口腔黏膜见2片指甲大小糜烂面,头面、躯干见大片红斑糜烂面及多个松弛性水疱,尼氏征阳性,四肢及会阴散在皮疹。间接免疫荧光检查(IIF)以猴食道上皮为底物,示棘细胞间偏下方IgG沉积,滴度1:80(正常值〈1:10),以鼠膀胱上皮为底物结果阴性。
出处
《中华检验医学杂志》
CAS
CSCD
北大核心
2008年第1期107-110,共4页
Chinese Journal of Laboratory Medicine
参考文献9
-
1Hertl M. Autoimmune Diseases of the skin: Pathogenesis, Diagnosis, Management. 2nd ed. Austria: Springer Wien New York, 2005:45-132.
-
2Burns T, Breathnach S, Cox N, et al. Rook's Textbook of Dermatology. 7th ed. London: Blackwell Science, 2004: 1-41, 58.
-
3Kanitakis J. Indirect immunofluorescence microscopy for the serological diagnosis of autoimmune blistering skin diseases: a review. Clin Dermatol, 2001,19:614-621.
-
4Freedberg IM, Elisen AZ, Wolff K, et al. Fitzpatrick' s Dermatology in General Medicine. 6th ed. New York : MC Graw Hill, 2003:543-632.
-
5Megahed M. Histopathology of Blistering Diseases with clinical, electron microscopic, immunological and molecular biological correlations. Berlin Heidelberg: Springer,2004 : 155-237.
-
6Amagai M, Komai A, Hashimoto T, et al. Usefulness of enzymelinked immunosorbent assay using recombinant desmogleins 1 and 3 for serodiagnosis of pemphigus. Br J Dermatol, 1999,140:351- 357.
-
7Zillikens D, Mascaro JM, Rose PA, et al. A highly sensitive enzyme-linked immunosorbent assay for the detection of circulating anti-BP180 autoantibodies in patients with bullous pemphigoid. J Invest Dermatol, 1997,109:679-683.
-
8Yoshida M, Hamada T, Amagai M, et al. Enzyme-linked immunosorbent assay using bacterial recombinant proteins of human BP230 as a diagnostic tool for bullous pemphigoid. J Dermatol Sci, 2006,41:21-30.
-
9McKee PH, Calonje E, Granter SR. Pathology of the skin, with clinical correlations. 3rd ed. Philadelphia: Elsevier, 2005 : 81- 170.
同被引文献11
-
1Baum S, Sakka N, Artsi O, et al. Diagnosis and classification of autoimmune blistering diseases[ J]. Autoimmun Rev, 2014, 13 (4-5) : 482-489.
-
2Otten JV, Hashimoto T, Hertl M, et al. Molecular diagnosis in autoimmune skin blistering conditions[ J]. Curt Mol Med, 2014, 14( 1 ) : 69-95.
-
3Bolognia JL, Jorizzo JL, Rapini RP. Dermatology [M]. Spain : Elsevier Ltd, 2008: 403-488.
-
4Goletz S, Hashimoto T, Zillikens D, et al. Anti-p200 pemphigoid [ J ]. J Am Aead Dermatol, 2014, 71 ( 1 ) : 185-191.
-
5Sehmidt E, Zillikens D. The diagnosis and treatment of autoimmune blistering skin diseases[ J]. Dtseh Arztebl Int, 2011, 108 (23) : 399-405, I-III.
-
6Arbache ST, Nogueira TG, Delgado L, et al. Immunofluorescence testing in the diagnosis of autoimmune blistering diseases: overview of 10-year experience [J]. An Bras Dermatol, 2014, 89(6): 885-88Q.
-
7van Beek N, Rentzsch K, Probst C, et al. Serological diagnosis of autoimmune bullous skin diseases : prospective comparison of the BIOCHIP mosaic-based indirect immunofluorescence technique with the conventional multi-step single test strategy [J]. Orphanet J Rare Dis, 2012, 7: 49.
-
8Mortazavi H, Khatami A, Seyedin Z, et al. Salivary desmoglein enzyme-linked immunosorbent assay for diagnosis of pemphigus vulgaris: a noninvasive alternative test to serum assessment [ J]. Biomed Res Int, 2015, 2015 : 698310.
-
9Lee EH, Kim YH, Kim S, et al. Usefulness of Enzyme-linked Immunosorbent Assay Using Recombinant BPI80 and BP230 for Serodiagnosis and Monitoring Disease Activity of Bullous Pemphigoid[J]. Ann Dermatol, 2012, 24(1): 45-55.
-
10Bing L, Xiping Z, Li L, et al. Levels of anti-BP180 NC16A IgE do not correlate with severity of disease in the early stages of bullous pemphigoid[ J ]. Arch Dermatol Res, 2015. [ Epub ahead of print ].
二级引证文献3
-
1布瓦杰尔.亚克亚,梁俊琴,康晓静.不同剂量丙种球蛋白冲击治疗重症寻常型天疱疮对免疫功能的影响及临床意义[J].新疆医科大学学报,2017,40(12):1522-1525. 被引量:2
-
2朱丹喜.炉甘石用于水疱大疱性皮肤病治疗与护理的临床分析[J].药品评价,2019,16(1):56-58. 被引量:3
-
3万立,刘美娜,陈金波,陈柳青.利格列汀相关的BP230型大疱性类天疱疮一例国内首报[J].中华皮肤科杂志,2021,54(2):136-138.
-
1林页新,宋力夫,邓列华,罗瑞圆,谢明,赵永铿暨南大学医学院附属医院.大疱性类天疱疮的免疫荧光检查[J].广东医学,1991,12(4):44-45.
-
2刘新媛,尹新江,李一雷,郭昊,李波,李久宏.结节性类天疱疮[J].临床皮肤科杂志,2013,42(11):675-677.
-
3金英花.15例寻常型天疱疮的护理[J].山东医药,2010,50(2):39-39. 被引量:2
-
4李秉煦,郭再康.40例掌跖脓疱病直接免疫荧光检查[J].中华皮肤科杂志,1990,23(6):404-405.
-
5林页新,宋力夫,邓列华,罗瑞园,赵永铿.疱疹样天疱疮的免疫荧光检查(附6例报告)[J].暨南大学学报(自然科学与医学版),1990,11(4):77-80.
-
6李强,赵玉铭,王雅坤,李晓东,肖毅,王珺,陈洪铎.大疱性类天疱疮患者头发毛囊中抗体检测的研究[J].中华皮肤科杂志,2005,38(2):125-125. 被引量:3
-
7严寒春,周勇.掌跖角化性湿疹应用钙泊三醇倍他米松的临床研究[J].中国医院用药评价与分析,2016,16(S1):158-158.
-
8杜甜甜,杨宝琦,王广进,周桂芝,刘红,张福仁.疱疹样天疱疮3例并文献复习[J].中国麻风皮肤病杂志,2016,32(2):93-95. 被引量:3
-
9唐书谦,叶庆佾,钟白玉.孢子丝菌病人血清的间接免疫荧光检查[J].第三军医大学学报,1997,19(5).
-
10丁杨峰,易雪梅,苏丽娜,楼玮.大疱性类天疱疮48例临床分析[J].中国麻风皮肤病杂志,2013,29(10):674-675. 被引量:2