摘要
免疫系统不仅具有抑制、杀伤肿瘤细胞的保护性功能,同时对肿瘤细胞亦有"塑形作用",使其获得弱的免疫原性而逃逸。干扰素-γ在肿瘤免疫编辑过程中发挥关键作用,但不同阶段其作用机制各不相同。
Organism immune system not only has protective functions such as suppressing and killing tumor cells, but also has the tumor-sculpting functions resulting in those tumor cells with weak immunogenicity escaping from immune pressure. Interferon-γ plays critical and different roles in different courses of tumor immunoeditting.
出处
《国际肿瘤学杂志》
CAS
2007年第12期890-893,共4页
Journal of International Oncology
基金
国家自然科学基金资助项目(30500590)
关键词
肿瘤
干扰素Ⅱ型
免疫疗法
免疫编辑
Neoplasms
Interferon type Ⅱ
Immunotherapy
Immunoediting