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乳腺癌微转移的分子诊断 被引量：2

Molecular diagnosis of micrometastasis in breast cancer
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摘要 在乳腺癌微转移的诊断中,病理学、免疫组织化学等常规方法敏感性不高,分子诊断学技术特别是逆转录一聚合酶链反应(RT-PCR)在微转移诊断中显示出了独特的优势。目前用于诊断乳腺癌微转移的生物学标记物主要有癌胚抗原、细胞角蛋白、人乳珠蛋白、多形上皮黏蛋白、基质金属蛋白酶、组织蛋白酶D、p53、表皮生长因子受体等。 Pathology, immunohistochemistry and other conventional methods are less sensitive in detection of micrometastasis in breast cancer. Molecular diagnostic technologies in particular reverse transcriptase polymerase chain reaction（RT-PCR） are superior in detection of micrometastasis. Now, the biological marks for breast cancer metastasis include carcinoembryonic antigen, cytokeratin, human mammaglobin, polymorphic epithelial mucin, matrix metalloproteinases, Cath-D, p53, epidermal growth factor recaptor, etc.
作者 胡贤春 邹学森
机构地区 江西省肿瘤医院肿瘤研究所
出处 《国际肿瘤学杂志》 CAS 2007年第12期923-926,共4页 Journal of International Oncology
关键词 乳腺肿瘤 肿瘤转移 肿瘤标记 生物学 分子诊断技术 逆转录聚合酶链反应 Breast neoplasms Neoplasm metastasis Tumor markers, biological Molecular diagnostic techniques Reverse transcriptase polymerase chain reaction
分类号 R737.9 [医药卫生—肿瘤]
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共引文献7

同被引文献43

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国际肿瘤学杂志
2007年 第12期

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