江苏省畜禽粪便中磺胺类药物残留特征

Residual Characteristics of Sulfanilamide in Animal Feces in Jiangsu Province

2005—2006年采集了江苏省各市不同种类的集约化畜禽养殖场共178个畜禽粪便样品,用柱前衍生法高效液相色谱荧光检测器,检测了样品中8种磺胺类药物(磺胺胍、磺胺、磺胺嘧啶、磺胺甲嘧啶、磺胺二甲嘧啶、磺胺间甲氧嘧啶、磺胺氯哒嗪、磺胺甲恶唑)残留情况。结果表明,磺胺类药物残留的检出率普遍较高,其中磺胺二甲嘧啶、磺胺氯哒嗪、磺胺检出率均高于50%。在平均残留量上磺胺甲嘧啶、磺胺氯哒嗪最大。8种药物检出总量变化较大,总量大于3000ng·g-1的小于5%,而总量小于200ng·g-1的约占50%,且各类药物同时检出的现象较为明显。在其地区分布上,苏北地区磺胺残留明显高于苏南,其中宿迁市残留量最高。在饲养类型上,奶牛的粪便磺胺残留最为严重。

178 samples of animal manure were collected in Jiangsu Province in 2005 to 2006, the residues of sulfagidine（SG）, sulfanilamide （SA）, sulfadiazine（SD）, sulfamerazine（SM1）, sulfadimidin（SM2）, sulfamonomethoxine（SMM）, sulfachloropyridazine（SCP）, sulfamethoxazole （SMZ） were determined by HPLC with fluorimetric detector after pre-column derivatization. The results revealed that the sulfanilamide all had a high level of occurrences of detection. The occurrences of detection of sulfadimidin, sulfachloropyridazine and sulfanilamide were higher than 50%. Sulfamerazine and sulfachloropyridazine had the highest pollution load. The data showed that the residue level with a concentration above 3 000 ng·g^-1 was less than 5%, while the pollution load with a concentration less than 200 ng·g^-1 was about 50%. Moreover, several sulfanilamides can be detected simultaneously in one feces sample. The pollution load of sulfanilamide residue in north-Jiangsu was higher than that in south-Jiangsu, and the city of Suqian had the highest pollution load. In terms of different kinds of animal feces, dairy manure had the highest pollution load.