冠脉病变特征和中医证候要素关系的研究

To Study Relationship between Coronary Artery Disease Characters and Syndrome Factor

目的:研究经冠脉造影证实的冠心病心绞痛患者的中医证候学和冠脉病变特征的关系。方法:用临床流行病学方法调研经冠脉造影证实的不稳定心绞痛患者。然后用SAS软件中的多元对应相关统计学方法进行分析。结果:①冠脉造影证实的冠心病患者中医证候要素和冠脉病变特征之间关系示:冠脉硬化组中与中医证候要素密切的先后顺序是气滞>热蕴>痰浊;冠脉A型病变特征与中医证候密切的先后顺序是痰浊>气滞>血瘀>阳虚;冠脉B型病变特征与中医证候密切的先后顺序是阴虚>气虚>血瘀>阳虚;冠脉C型病变特征是血瘀>寒凝>阳虚>气虚。②冠心病冠脉病变特征和证候要素相兼分布表中示:冠脉无病变组主要以单证和两证相兼的证候为主;冠脉A行病变特征组主要以证候要素2证相兼和3证相兼为主;冠脉B型病变特征组主要以证候要素3证相兼和4证相兼为主;冠脉C型病变特征组主要以证候要素3证相兼、4证相兼和4证以上相兼为主。结论:随着冠脉病变加重,痰浊、血瘀证和阴虚证与冠脉病变的程度的相关性越来越强,证候之间的组合趋于复杂化。

Objective： To study relationship between morbid characteristic of coronary artery disease and syndrome factor, Method： Clinical epidemiological method was used to investigate unstable angina pectoris patients confirmed by coronary visualization. Mullty correspongding - tel ation method was used. Result ： ①Relationship between syndrome factor of CAD patients with morbid characteristic of CAD：the sequence related to patterns in hardening coronary artery group was：qi stagnation 〉 heat 〉 phlegm turbidity ;the sequence related to patterns in coronary artery diease group with ＂A＂type was： phlegm turbidity 〉 qi stagnation 〉 blood stasis 〉 yang deficiency ; the sequence related to patterns in coronary artery diease group with ＂B＂ type was ：yin deficiency 〉 qi deficiency 〉 blood stasis 〉 yang deficiency; the sequence related to patterns in coronary artery diease group with ＂C＂ type was ：blood stasis 〉 cold coagulation 〉 qi deficiency 〉 yang deficiency. ②Relationship between morbid CAD of different type and syndrome factor distribution： single syndrome factor and two factors were main in hardening coronary artery group; two syndrome factors and three factors were main in coronary artery diease group with ＂A＂type; three syndrome factors and four factors were main in coronary artery diease group with ＂B＂ type;three syndrome factors, four factors and four more factors were main in coronary artery diease group with ＂C＂type. Conclusion： With coronary artery morbidity aggravating, phlegm turbidity, blood stasis and yin deficiency had close relation between morbid degree of coronary artery, syndrome factor combination became complicated.