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乳腺癌相关microRNA的研究进展 被引量：3

MicroRNA and breast cancer
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摘要 MicroRNAs是一类内源性稳定的非编码小分子RNA，在基因转录后水平调控细胞的增殖、凋亡和分化相关的基因表达，与肿瘤的发生和发展密切相关。本文综述了乳腺癌相关的microRNA，如何通过调控目标基因的表达以控制乳腺癌的发展。 MicroRNAs （miRNAs） are a class of evolutionarily conserved, endogenous, small, noncoding RNA, which posttranscriptionally control the proliferation, differentiation, apoptosis and ontogeny of cells , etc. MicroRNAs also are colsely interrelated with the pathogenesis and development of cancer. We reviewed the microRNAs related with breast cancer and bow they controlled the development of breast cancer through regulating the expression of targeted genes.
作者 李志华 姚和瑞 苏逢锡
机构地区 中山大学附属第二医院乳腺肿瘤中心 中山大学附属第二医院肿瘤科
出处 《国际外科学杂志》 2008年第1期57-59,共3页 International Journal of Surgery
基金 国家自然科学基金项目（No.30471977）
关键词 MICRORNA 乳腺癌 基因调控 microRNA breast cancer gene control
分类号 R737 [医药卫生—肿瘤]
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参考文献21

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共引文献1

同被引文献55

  • 1侯晓玮,王雅杰,王梅,朱玉兆,李永梅.同源异型盒基因HOXD10在乳腺癌组织中的表达及其临床病理意义[J].中国癌症杂志,2007,17(6):448-452. 被引量：5
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二级引证文献12

国际外科学杂志
2008年 第1期

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