儿童重症监护室呼吸机相关肺炎病原学分析

Etiological analysis of ventilator-associated pneumonia in PICU

目的:探讨儿童重症监护室(PICU)呼吸机相关肺炎(VAP)的临床病原学特点。方法:对156例PICU机械通气患儿的临床资料、病原菌构成和药敏试验结果进行分析。结果:156例机械通气患儿中,66例发生VAP,发生率为42.4%,早发性VAP病原菌以革兰阳性菌为主,晚发性VAP以革兰阴性菌为主,耐药性较高。结论:明确VAP的发病因素和致病菌,有利于合理使用抗生素,预防VAP。

Objective a To analyze the clinical and etiological characteristics and bactcrial susceptibility of children with ventilator-associated pneumonia in PICU. Methods： The mechanically ventilated patients in PICU of Xi＇an children＇s hospital were studied retrospectivly in regard to clinical data ,pathogen analysis and bacterial susceptibility. Results： Among the 156 ventilated childen, 66 cases of VAP were diagnosed with the incidence rate of 42% . The major pathogens of early onset VAP were identified as Gram-positive bacteria ;Gram-negative pathogens predominated in late onset VAP. Conclusion.. Early detection of the VAP risk factors and pathogens will facilitate antibiotic therapy to prevent and treat VAP.