重组人α-2b干扰素治疗婴幼儿秋季腹泻98例临床观察

Observation on α-2b interferon in treatment of autumn diarrhea in infants

目的探讨重组人α-2b干扰素(利分能)治疗婴幼儿秋季腹泻的疗效。方法将秋季腹泻患儿(均为住院患儿)98例,随机分为治疗组(49例)和对照组(49例),治疗组除应用常规治疗措施外另用干扰素肌注;对照组采用常规治疗。观察用药后临床治疗效果。结果治疗组止泻时间(50.52±9.35)h,对照组为(58.45±11.14)h,经统计学处理两组差异有统计学意义(P<0.05)。结论干扰素在治疗婴幼儿秋季腹泻病方面可取得良好效果,可以在临床上采用。

Objective To investigate the therapeutic effect of α-2b interferon（α-2bIFN） in the treatment of autumn diarrhea in infants. Methods Ninety-eight infant with autumn diarrhea were randomly divided into 2 groups,the therapy group（49 cases） and the control group（35 cases）. The therapy group was given α-abIFN with muscular injection except routine therapy. The control group was given routine therapy. The therapeutic effects were investigated and compared after treatment. Results The time of ceasing diarrhea was （50.52 ± 9.35）h in the timetreatment group and （58.45 ±11.14）h in the control group respectively, with statistical difference（P〈0.05）. Conclusion Using interferon in treating infant autumn diarrhea is well effective and worthy of application to clinical practice.