多软膜下横切术治疗顽固性癫痫116例临床应用

116 Cases Report or Multiple Subpial Transection to theSurgical Treatment of Intractable Epilepsy

自１９９１年元月至１９９６年１２月，共实施多软膜下横切术１１６例，随访１￣５年者１００例，发作完全控制６２例（占６２％），明显（发作减少７５％以上）２０例（２０％）减少（发作减少５０％以上）１２例（占１２％），无变化６例（占６％），总有效率为９４％，显效率８２％，未发现任何功能损害，这一结果表明，ＭＳＴ治疗顽固性癫痫十分有效，可替代传统的痫灶切除术，但长期疗效仍需进一步观察。

On the hasis of experimental study, we have performed multiple subpial transec-tion (MST) in 116 intractable epiieptic patients since 1991, 100 patients were followed up for 1 to5 years. Complete contral of seizure was abtained in 62 cases (62%), significant reduce (morethan 75% ) in 20 (20%), reduce (more than 50% ) in 12 (12%), and no change in 6 (6% ). Totaleffective rate was 94% and the significant effective rate was 82%, No functional defect was foundin any patients. The results indicate that MST is quite a good approach to the surgical treatmentof intractable epilepsy. lt is suggested that MST could instead of some standard excisionaltherepy. But the long-term effect should be confirmed after further observation.