期刊文献+

泛耐药鲍曼不动杆菌交叉感染的防控策略 被引量:21

The prevention and control of pan-drug resistant acinetobacter baumanii cross-infection
下载PDF
导出
摘要 目的总结呼吸重症监护病房(RICU)防控泛耐药(PDR)鲍曼不动杆菌交叉感染的经验,探讨泛耐药鲍曼不动杆菌以及其他泛耐药株交叉感染防控的新思路及有效方法。方法采用脉冲场凝胶电泳(PFGE)方法对分离自RICU的泛耐药鲍曼不动杆菌进行分子分型,提出"降阶梯防控策略"并实施。结果自RICU 4例患者检出的PDR鲍曼不动杆菌PFGE图形一致,存在交叉感染;采取降阶梯防控措施,未再有其他患者感染PDR鲍曼不动杆菌。结论4例RICU患者存在PDR鲍曼不动杆菌交叉感染,采取"降阶梯防控策略"对控制泛耐药鲍曼不动杆菌以及其他泛耐药株交叉感染有重大意义。 Objective To summarize the experience of prevention and control of pan-drug resistant acinetobacter baumanii cross-infection, in order to create a novel thought of the effective prevention and control of related PDR pathogens, including A. baumanii. Methods Pulsed-field gel electrophoresis ( PFGE ) was applied to analyze the 5 PDR A. baumanii strains isolated from 4 patients in RICU. According to the hazard of acquiring cross-infection, we adopted " De-escalation prevention and control strategy" to RICU patients. Results PFGE analysis showed 5 PDR A. baumanii were identical, which confirmed cross-infection between the 4 patients. There was no more patient acquiring PDR A. baumanii infection in RICU anymore. Conclusion "De-escalation prevention and control strategy" has important meaning in the prevention and control of all related PDR pathogens including A. baumanii.
出处 《上海护理》 2008年第1期10-13,共4页 Shanghai Nursing
关键词 泛耐药鲍曼不动杆菌 交叉感染 降阶梯防控策略 Pan-drug resistant acinetobacter baumanii Cross-infection De-escalation prevention and control strategy
  • 相关文献

参考文献8

  • 1[1]Richet HM.Nosocomial gram-negative bacilli:they are back! Dealing with Acinetobacter.44th Interscience Conference on Antimicrobial Agents and Chemotherapy[C].October 30-November 2,2004,Washington DC.
  • 2王辉,孙宏莉,宁永忠,杨启文,陈民钧,朱元珏,徐英春,谢秀丽.不动杆菌属多重耐药及泛耐药的分子机制研究[J].中华医学杂志,2006,86(1):17-22. 被引量:183
  • 3[3]Manikal VM,Landman D,Saurina G,et al.Endemic carbapenem-resistant Acinetobacter species in Brooklyn,New York:citywide prevalence,interinstitutional spread,and relation to antibiotic usage[J].Clin Infect Dis,2000,31(1):101-106.
  • 4[4]Zarrulli R,Crispino M,Bagattini M,et al.Molecular epidemiology of sequential outbreaks of Acinetobacter baumannii in an intensive care unit shows the emergence of carbapenem resistance[J].J Clin Microbiol,2004,42(3):946-953.
  • 5[5]Hsueh PR,Teng LJ,Chen CY,et al.Pandrug-resistant Acinetobacter baumannii causing nosocomial.infections in a university hospital[J].Taiwan.Emerg Infect Dis,2002,8(8):827-832.
  • 6[6]Kuo LC,Yu CJ,Lee LN,et al.Clinical features of pandrug-resistant Acinetobacter baumannii bacteremia at a university hospital in Taiwan[J].J Formos Med Assoc,2003,102(9):601-606.
  • 7[8]Tenover FC,Arbeit RD,Goering RV,et al.Interpreting chromosomal DNA restriction patterns produced by pulsedfield gel electrophoresis:criteria for bacterial strain typing[J].J Clin Microhiol,1995,33(9):2233-2239.
  • 8[10]Falagas ME,Bliziotis IA,Kasiakou SK,et al.Outcome of infections due to pandrug-resistant (PDR) Gramnega-tive bacteria[J].BMC Infect Dis,2005,5(1):24.

二级参考文献17

  • 1王辉,孙宏莉,廖康,陈冬梅,王清涛,王飞燕,陈民钧,朱元珏.北京和广州地区四家医院不动杆菌碳青霉烯酶基因型研究[J].中华检验医学杂志,2005,28(6):636-641. 被引量:121
  • 2Clinical and Laboratory Standards Institute. 2005. Performance standards for antimicrobial susceptibility testing; fifteenth informational supplement. Clinical and Laboratory Standards Institute, Wayne, Pa.
  • 3Tenover FC, Arbeit RD, Goering RV, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. J Clin Microbial,1995, 33 : 2233-2239.
  • 4Levesque C, Piche L, Larose C, et al. PCR mapping of integrons reveals several novel combination of resistance genes. Antimicrob Agents Chemother, 1995, 39 : 185-191.
  • 5Jeon BC, Jeong H, Bae K, et al. Investigation of a nosocomial outbreak of imipenem-resistant Acinetobacter baumannii producing OXA-23 β-lactamase in Korea. J Clin Microb, 2005, 43:2241-2245.
  • 6Dalla-Costa LM, Coelho JM, Souza HAPHM, et al. Outbreak of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 enzyme in Curitiba, Brazil. J Clin Microb, 2003, 41:3403-3406.
  • 7Villers D, Espase E, Coste-Burel M, et al. Nosocomial Acinetobacter baumannii infections: microbiological and clinical epidemiology. Ann Intern Med, 1998, 129: 182-189.
  • 8Manikal VM, Landman D, Saurina G, et al. Endemic carbapenem-resistant Acinetobacter species in Brooklyn, New York.- citywide prevalence, interinstitutional spread, and relation to antibiotic usage. Clin Infect Dis, 2000, 31 : 101-106.
  • 9Kuo L, Teng L, Yu C, et al. Dissemination of a clone of unusual phenotype of pandrug-resistant Acinetobacter baumannii at a university hospital in Taiwan. J Clin Microbiol, 2004, 42: 1759-1763.
  • 10Zarrulli R, Crispino M, Bagattini M, et al. Molecular epidemiology of sequential outbreaks of Acinetobacter baumannii in an intensive care unit shows the emergency of carbapenem resistance. J Clin Microbiol, 2004, 42: 946-953.

共引文献182

同被引文献186

引证文献21

二级引证文献178

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部